Contoral Health

Contoral Health

Continuous oral delivery represents a groundbreaking advancement in drug delivery. Currently, continuous drug delivery is typically limited to invasive pumps, subcutaneous devices, and buccal patches. The Contoral device introduces a novel method by providing continuous delivery directly in the mouth.

Contoral’s first device targets Xerostomia, or Dry Mouth, a common side effect of cancer therapies that can lead to swallowing and sleep difficulties, as well as a decline in oral health. Existing treatments like gels, rinses, and sprays wear off quickly.

The device is a small, disposable cartridge pre-filled with an oral gel, powered by a spring-loaded syringe that releases the gel slowly through a small opening. The cartridge is held in place by a custom oral appliance, similar to a dental retainer. The device can be worn anytime but is most convenient overnight, as it must be removed while eating. The gel contains active enzymes, including xylitol, which stimulate the salivary glands.

Contoral Device

Figure 1: Contoral Device Prototypes

Figure 2: Custom Oral Appliance

To obtain the Contoral device, patients will visit a dentist in order to have a custom-made appliance. The device can also be attached to other oral appliances such as dentures, false teeth/crowns, or dental bites.

The Contoral device is currently under development.  In the future, Contoral plans to expand its technology to treat conditions such as Parkinson’s Disease, and eventually explore other areas like neurology and pain management.

For more information, please contact info@contoralhealth.com.sg.

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Contact Information
  • Lee Kong Chian School of
    Medicine,
    Clinical Sciences Building
    11 Mandalay Road #16-01
    Singapore 308232

  • +65 6904 1401
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co11ab Novena (co11ab) is a Bio MedTech incubator – forged through a tripartite alliance between Nanyang Technological University, Singapore (NTU Singapore), Agency for Science, Technology, and Research (A*STAR), and National Healthcare Group (NHG) – which aims to nurture and support the translational development of biomedical technologies. Our key focus areas are biotech, medtech and digital health.